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U.S. Department of Health and Human Services

GRAS Notices
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GRN No. 1282

Rebaudioside M produced by enzymatic treatment of rebaudioside A purified from the leaves of Stevia rebaudiana (Bertoni) Bertoni

Intended Use: Intended for use as a general-purpose sweetener in foods excluding infant formula and products under the U.S. Department of Agriculture's jurisdiction, at levels determined by current good manufacturing practice.
Basis: Scientific procedures
Notifier: Zhucheng Haotian Pharm Co., Ltd.
Notifier Address: Xinxing Town, Zhucheng City
Shandong Province, 262218
CHINA
GRAS Notice (releasable information): GRN 1282 with amendments (in PDF) (9.5 MB)
Date of closure: Jan 12, 2026
FDA's Letter: FDA has no questions (in PDF) (257 kB)
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