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U.S. Department of Health and Human Services

Final Rules: Food Additives and Color Additives

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Petition(s): FAP 3B4346

Indirect Food Additives: Adhesives and Components of Coatings

Petitioner: Dow Corning Corp.
Docket number (legacy and/or former docket number(s)): (92F-0443)
Subject additive and intended use: amending the food additive regulations to provide for the safe use of 1,2-dibromo-2,4-dicyanobutane (DBDCB) and a mixture of 5-chloro-2-methyl-4-isothiazolin-3-one (CMI) and 2-methyl-4-isothiazolin-3-one (MI), optionally containing magnesium nitrate, as antimicrobial agents in emulsion-based silicone coating formulations.
21 CFR* affected: 175.300; Resinous and polymeric coatings.
175.320; Resinous and polymeric coatings for polyolefin films.
176.170; Components of paper and paperboard in contact with aqueous and fatty foods.
176.180; Components of paper and paperboard in contact with dry food.
Substance(s)*, (CAS Registry® No.):
  • 1,2-dibromo-2,4-dicyanobutane (DBDCB), (35691-65-7)
  • mixture of 5-chloro-2-methyl-4-isothiazolin-3-one (CMI) 26172-55-4 and 2-methyl-4-isothiazolin-3-one (MI) 2628-20-4, optionally containing magnesium nitrate, (10377-60-3)
  • Federal Register publication history: Feb 12, 1993; 58 FR 8290; Notice
    Jul 2, 1998; 63 FR 36246; Notice
    Dec 24, 1998; 63 FR 71294; Notice (Amendment)
    Feb 11, 2000; 65 FR 6889; Final Rule; Effective date: Feb 11, 2000


     

    *Definitions

    • 21 CFR: Title 21 of the Code of Federal Regulations.
    • Substance: The name of the substance listed in the CFR.
    • CAS Registry® No.: Chemical Abstract Service (CAS) Registry Number® for the substance.
    • Petitions (see also Questions and Answers About the Petition Process)
      • FAP: Food Additive Petition
      • CAP: Color Additive Petition
      • GRP: GRAS Affirmation Petition (replaced by GRAS Notification Program in 1998)
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