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U.S. Department of Health and Human Services

GRAS Notices
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GRN No. 1295

Brazzein preparation produced by Komagataella phaffii GS115 expressing a gene encoding for brazzein from Pentadiplandra brazzeana

Intended Use: Intended for use as a general-purpose sweetener in foods at levels consistent with good manufacturing practices (excluding use in infant formula and products under the jurisdiction of the United States Department of Agriculture).
Basis: Scientific procedures
Notifier: MicroFarmtory LLC
Notifier Address: 163 Capitol Ave, Suite 413, C1088
Cheyenne, WY 82001
GRAS Notice (releasable information): GRN 1295 (in PDF) (10.1 MB)
  Part 2: GRN 1295 amendments (in PDF) (5.8 MB)
Date of closure: Jun 23, 2026
FDA's Letter: FDA has no questions (in PDF) (263 kB)
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