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U.S. Department of Health and Human Services

GRAS Notices
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GRN No. 1201

Lipase enzyme preparation produced by Komagataella phaffii expressing a gene encoding lipase from Yarrowia lipolytica

Intended Use: Intended for use as an enzyme at up to 95.1 mg Total Organic Solids (TOS)/kg raw material in the production of cheese, enzyme-modified dairy ingredients, and plant-based analogues of milk and milk products.
Basis: Scientific procedures
Notifier: Chr. Hansen A/S
Notifier Address: Boege Allé 10-12
Hoersholm 2970
Denmark
GRAS Notice (releasable information): GRN 1201 with amendments (in PDF) (6.2 MB)
Date of closure: Mar 10, 2025
Date of FDA’s corrected letter: Jul 3, 2025
FDA's Letter: FDA has no questions (183 kB)
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