Substances Added to Food (formerly EAFUS)

GRN No. 451

Intended Use:	As a source of ascorbic acid (vitamin C) in beverages and beverage bases, breakfast cereals, chewing gum, coffee and tea, grain products, processed fruits and fruit juices, and medical foods at levels of up to 500 milligrams of vitamin C per serving
Basis:	Scientific procedures
Notifier:	The Ester C Company
Notifier Address:	6735 Inter-Cal Way Prescott, AZ 86301
Date of filing:	Dec 12, 2012
GRAS Notice (releasable information):	GRN 451 (in PDF)6.3 MB
Date of closure:	Aug 5, 2013
FDA's Letter:	FDA has no questions

CAS Reg. No. (or other ID): Chemical Abstract Service (CAS) Registry Number® for the substance or a numerical code assigned by HFP to those substances that do not have a CAS Registry Number (977nnn-nn-n series).
Substance: The name of the ingredient as recognized by HFP.
Used for^† (Technical Effect): The physical or technical effect(s) the substance has in or on food; see 21 CFR 170.3(o) for definitions.
21 CFR: Title 21 of the Code of Federal Regulations.
FEMA No.: The trade association, Flavor and Extract Manufacturers Association (FEMA), has established expert panels to evaluate and make independent determinations on the GRAS status of flavoring substances. The FEMA number is provided here as a reference to FEMA’s GRAS assessments.
- The GRAS Pub. No. is the FEMA GRAS™ publication number.
- NLFG is no longer FEMA GRAS™.
- For more information about FEMA GRAS, see About the FEMA GRAS™ Program <> .
JECFA: The Joint Expert Committee on Food Additives (JECFA) is an international expert scientific committee that is administered jointly by the Food and Agriculture Organization of the United Nations (FAO) and the World Health Organization (WHO). See JECFA Specifications for Flavourings <>

For a substance to be used as a color additive in the US, it must be authorized by a regulation in 21 CFR Part 73, 74, or 82.